USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: SAHH_HUMAN USC-OGP 2-DE database:  SAHH_HUMAN SAHH_HUMAN General information about the entry View entry in simple text format Entry name SAHH_HUMAN Primary accession number P23526 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Adenosylhomocysteinase; Short=AdoHcyase; EC=3.3.1.1; AltName: Full=S-adenosyl-L-homocysteine hydrolase;. Gene name Name=AHCY Synonyms=SAHH Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1177: pI=6.18; Mw=44777 Cross-references UniProtKB/Swiss-Prot P23526; SAHH_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SAHH_HUMAN Primary accession number P23526 Secondary accession number(s) A8K307 B3KUN3 E1P5P2 F5H737 Q96A36 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 187) Name and origin of the protein Description RecName: Full=Adenosylhomocysteinase; Short=AdoHcyase; EC=3.3.1.1; AltName: Full=S-adenosyl-L-homocysteine hydrolase; Gene name Name=AHCY Synonyms=SAHH Encoded on Name=AHCY; Synonyms=SAHH Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Hydrolase; NAD; One-carbon metabolism; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M61831; AAA51681.1; -; mRNA EMBL M61832; AAA51682.1; -; mRNA EMBL BT006697; AAP35343.1; -; mRNA EMBL AK097610; BAG53495.1; -; mRNA EMBL AK290422; BAF83111.1; -; mRNA EMBL AL356299; CAC09528.1; -; Genomic_DNA EMBL CH471077; EAW76279.1; -; Genomic_DNA EMBL CH471077; EAW76280.1; -; Genomic_DNA EMBL BC010018; AAH10018.1; -; mRNA EMBL BC011606; AAH11606.1; -; mRNA CCDS CCDS13233.1; -. [P23526-1]; . CCDS CCDS54457.1; -. [P23526-2]; . PIR A43629; A43629; . RefSeq NP_000678.1; NM_000687.3. [P23526-1]; . RefSeq NP_001155238.1; NM_001161766.1. [P23526-2]; . RefSeq NP_001309013.1; NM_001322084.1. [P23526-2]; . RefSeq NP_001309014.1; NM_001322085.1. [P23526-2]; . RefSeq XP_005260374.1; XM_005260317.2. [P23526-2]; . RefSeq XP_011526961.1; XM_011528659.1. [P23526-2]; . RefSeq XP_016883197.1; XM_017027708.1. [P23526-1]; . RefSeq XP_016883198.1; XM_017027709.1. [P23526-1]; . UniGene Hs.388004; -; . PDB 1A7A; X-ray; 2.80 A; A/B=1-432 PDB 1LI4; X-ray; 2.01 A; A=1-432 PDB 3NJ4; X-ray; 2.50 A; A/B/C/D=1-432 PDB 4PFJ; X-ray; 2.30 A; A/B=1-432 PDB 4PGF; X-ray; 2.59 A; A/B=1-432 PDB 4YVF; X-ray; 2.70 A; A/B=1-432 PDBsum 1A7A; -; . PDBsum 1LI4; -; . PDBsum 3NJ4; -; . PDBsum 4PFJ; -; . PDBsum 4PGF; -; . PDBsum 4YVF; -; . ProteinModelPortal P23526; -; . SMR P23526; -; . BioGrid 106696; 73; . IntAct P23526; 25; . MINT MINT-5000523; -; . STRING 9606.ENSP00000217426; -; . BindingDB P23526; -; . ChEMBL CHEMBL2664; -; . DrugBank DB03273; 3'-Oxo-Adenosine; . DrugBank DB03769; D-Eritadenine; . DrugBank DB02325; Isopropyl Alcohol; . GuidetoPHARMACOLOGY 1233; -; . iPTMnet P23526; -; . PhosphoSitePlus P23526; -; . SwissPalm P23526; -; . BioMuta AHCY; -; . DMDM 20141702; -; . REPRODUCTION-2DPAGE IPI00012007; -; . EPD P23526; -; . MaxQB P23526; -; . PaxDb P23526; -; . PeptideAtlas P23526; -; . PRIDE P23526; -; . DNASU 191; -; . Ensembl ENST00000217426; ENSP00000217426; ENSG00000101444. [P23526-1]; . Ensembl ENST00000538132; ENSP00000442820; ENSG00000101444. [P23526-2]; . GeneID 191; -; . KEGG hsa:191; -; . UCSC uc002xai.4; human. [P23526-1]; . CTD 191; -; . DisGeNET 191; -; . GeneCards AHCY; -; . HGNC HGNC:343; AHCY; . HPA HPA041225; -; . HPA HPA044675; -; . MalaCards AHCY; -; . MIM 180960; gene; . MIM 613752; phenotype; . neXtProt NX_P23526; -; . OpenTargets ENSG00000101444; -; . Orphanet 88618; Psychomotor retardation due to S-adenosylhomocysteine hydrolase deficiency; . PharmGKB PA24636; -; . eggNOG KOG1370; Eukaryota; . eggNOG COG0499; LUCA; . GeneTree ENSGT00390000003626; -; . HOGENOM HOG000227987; -; . HOVERGEN HBG005041; -; . InParanoid P23526; -; . KO K01251; -; . OMA VHDKYPQ; -; . OrthoDB EOG091G06EB; -; . PhylomeDB P23526; -; . TreeFam TF300415; -; . BRENDA 3.3.1.1; 2681; . Reactome R-HSA-156581; Methylation; . Reactome R-HSA-1614635; Sulfur amino acid metabolism; . Reactome R-HSA-2408508; Metabolism of ingested SeMet; Sec; MeSec into H2Se SABIO-RK P23526; -; . UniPathway UPA00314; UER00076; . ChiTaRS AHCY; human; . EvolutionaryTrace P23526; -; . GenomeRNAi 191; -; . PRO PR:P23526; -; . Proteomes UP000005640; Chromosome 20; . Bgee ENSG00000101444; -; . CleanEx HS_AHCY; -; . Genevisible P23526; HS; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0043005; C:neuron projection; IEA:Ensembl; . GO GO:0005634; C:nucleus; IEA:Ensembl; . GO GO:0004013; F:adenosylhomocysteinase activity; TAS:UniProtKB; . GO GO:0030554; F:adenyl nucleotide binding; IEA:Ensembl; . GO GO:0051287; F:NAD binding; IEA:Ensembl; . GO GO:0002439; P:chronic inflammatory response to antigenic stimulus; IEA:Ensembl; . GO GO:0042745; P:circadian sleep/wake cycle; IEA:Ensembl; . GO GO:0071268; P:homocysteine biosynthetic process; IEA:Ensembl; . GO GO:0032259; P:methylation; TAS:Reactome; . GO GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW; . GO GO:0001666; P:response to hypoxia; IEA:Ensembl; . GO GO:0007584; P:response to nutrient; IEA:Ensembl; . GO GO:0019510; P:S-adenosylhomocysteine catabolic process; IEA:Ensembl; . GO GO:0033353; P:S-adenosylmethionine cycle; IBA:GO_Central; . GO GO:0000096; P:sulfur amino acid metabolic process; TAS:Reactome; . CDD cd00401; SAHH; 1; . Gene3D 3.40.50.720; -; 1; . HAMAP MF_00563; AdoHcyase; 1; . InterPro IPR000043; Adenosylhomocysteinase-like; . InterPro IPR015878; Ado_hCys_hydrolase_NAD-bd; . InterPro IPR016040; NAD(P)-bd_dom; . InterPro IPR020082; S-Ado-L-homoCys_hydrolase_CS; . PANTHER PTHR23420; PTHR23420; 1; . Pfam PF05221; AdoHcyase; 1; . Pfam PF00670; AdoHcyase_NAD; 1; . PIRSF PIRSF001109; Ad_hcy_hydrolase; 1; . SMART SM00996; AdoHcyase; 1; . SMART SM00997; AdoHcyase_NAD; 1; . SUPFAM SSF51735; SSF51735; 1; . TIGRFAMs TIGR00936; ahcY; 1; . PROSITE PS00738; ADOHCYASE_1; 1; . PROSITE PS00739; ADOHCYASE_2; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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